Construction of plant transformation vectors designed by CropDesign's "click and clone" software is partially automated using robots. Robotized cloning is a key component of the TraitMill's high-throughput specifications.

CropDesign has developed and licensed several proprietary tools for high throughput gene cloning and gene expression modulation. Genes are generally tested in combination with a suite of constitutive and organ-specific promoters. The company has more than 40 fully characterized cereal promoters.